Apparently the game is separated into five different Scenarios split between the Five Eras, and at current looks like it will be accommodating 3 different characters in each era?

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KENN, the Japanese voice actor for Yuuki Juudai (Jaden Yuki to you more dub aware fans) will be returning to do new voice work.

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However, don’t expect Yugi’s Japanese VA to show up, as apparently his contract with the talent agency Johnny and Associates prevents him from doing anything other than the TV shows and movies.